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. 2015 Oct 20;5(10):e661. doi: 10.1038/tp.2015.161

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Copyright © 2015 Macmillan Publishers Limited

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Hepatic expression of PGRMC1/INSIG/SCAP/SREBP mRNA in rats after 4-week treatment with different antipsychotic drugs (a, b); add-on MIF medication with AAPD monotherapy (c, d) using real-time qPCR. *P<0.05, **P<0.01 and ***P<0.0001 as compared with controls. ⁺P<0.05 and ⁺⁺P<0.01 in parentheses as compared with corresponding AAPD monotherapy group. Relative expression values were presented as a normalized ratio to the β-actin mRNA level. AAPD, atypical antipsychotic drug; ARI, aripiprazole; CLO, clozapine; CLO+MIF, clozapine with add-on MIF treatment; HAL, haloperidol; MIF, mifepristone; NC, normal control; qPCR, quantitative polymerase chain reaction; RIS, risperidone; RIS+MIF, risperidone with add-on MIF treatment.