2. Types of infection.
| Study | Number of participants analysed | Possible or probable infection | Localised infections (excluding oral candida) | Systemic infections (Bacteraemia or fungaemia | |||
| Therapeutic granulocytes | Control | Therapeutic granulocytes | Control | Therapeutic granulocytes | Control | ||
| Alavi 1977 | 31 (62 febrile episodes) |
2 participants | 3 participants | 2 participants 2 Abscess or cellulitis 0 Urinary tract infection |
2 participants 1 Abscess or cellulitis 1 Urinary tract infection |
10 participants 1 E. coli 4 Klebsiella 0 Pseudomonas 2 Gram negative (other) 2 Gram‐positive 1 Candidaemia |
14 participants 4 Pseudomonas 4 Klebsiella 2 E. coli 1 Gram‐negative (other) 3 Gram‐positive 0 Candidaemia |
| Bow 1984 | 24 | 13 | 11 | 0 | 0 | 0 | 0 |
| Herzig 1977 | 27 (30 septic episodes) |
0 | 0 | 0 | 0 | 9 E. coli 2 Klebsiella 2 Pseudomonas 0 Proteus 0 Neisseria 3 Mixed gram‐negative |
4 E. coli 4 Klebsiella 1 Pseudomonas 1 Proteus 1 Neisseria 3 Mixed gram‐negative |
| Higby 1975 | 27 (aged < 45 years) |
4 | 4 | 3 Pneumonia 4 Abscess (other) 4 Perirectal abscess 1Urinary tract infection 0 Other |
4 Pneumonia 1 Abscess (other) 3 Perirectal abscess 3 Urinary tract infection 1 Other |
5 Bacteraemia | 6 Bacteraemia |
| Price 2015 | 97 | 11 Probable pulmonary fungal | 9 Probable pulmonary fungal | 2 Pulmonary fungal 3 Sinus fungal 1 Skin/soft tissue fungal 2 Other fungal 5 Typhilitis 8 Invasive bacterial |
2 Pulmonary fungal 0 Sinus fungal 2 Skin/soft tissue fungal 4 Other fungal 2 Typhilitis 13 Invasive bacterial |
14 Bacteraemia 3 Candidaemia 0 Fungaemia (other) |
11 Bacteraemia 6 Candidaemia 2 Fungaemia (other) |
| Scali 1978 | 25 | 2 | 3 | 3 Pneumonia 5 Abscess 0 Other |
1 Pneumonia 0 Abscess 3 Other |
3 Bacteraemia | 5 Bacteraemia |
| Seidel 2008a | 67 (72 episodes) |
Probable fungal infection. Aspergillus 32, Aspergillus & Candida 1, Other 3 Unidentified infection 12 |
Detected fungal infection. Aspergillus 15, Candida 3, Both 1 Detected bacterial. Pseudomonas 2, Staph. aureus 1, Other (not defined) 2 |
||||
| Vogler 1977 | 30 | 0 | 0 | 7 (perirectal, skin, pulmonary, renal tract) |
4 Pseudomonas 8 Other |
3 Pseudomonas 8 Other |
|
| Winston 1982a | 95 | 0 | 0 | 4 Pneumonia 7 Celluluitis/abscess |
5 Pneumonia 3 Celluluitis/abscess |
12 E. coli 11 Klebsiella 4 Pseudomonas 0 Proteus 1 Gram negative (other) 4 Mixed gram‐negative 5 Gram‐positive |
10 E. coli 5 Klebsiella 12 Pseudomonas 1 Proteus 3 Gram negative (other) 5 Mixed gram‐negative 3 Gram‐positive |