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. 2016 Apr 29;2016(4):CD005339. doi: 10.1002/14651858.CD005339.pub2

7. Other adverse events.

Study Number of participants receiving granulocyte transfusions Donor events Recipient events
Alavi 1977 12 Not reported 2 participants developed urticaria
28/176 (16%) transfusions associated with fever
12/176 (7%) of transfusions associated with chills but no fever
Herzig 1977 15 Not reported < 10/68 (15%) obtained by continuous flow centrifugation
> 96/129 (75%) obtained by leukapheresis were associated with transfusion reactions (fevers or chills)
Higby 1975 17 14/67 faintness
1/67 chills
4/67 nausea
2/67 fainted
1/67 arm pain
40/68 transfusions associated with fever
Price 2015 56 Not reported 41% of participants had mild to moderate reactions (grade 1 to 2) ‐ fever, chills or changes in blood pressure
9 more severe reactions (grade 3 to 4), 6 hypoxia, 1 tachycardia, 1 hypotension, 1 allergic reactions
Vogler 1977 32 2 chills
3 periorbital tingling
3 faintness
2 headache
No dyspnoea
No febrile reactions
Winston 1982a 48 Not reported 19 participants, 12 had fever and chills; 2 had fever, chills and a rash; 1 rash only; 4 dyspnoea