7. Other adverse events.
Study | Number of participants receiving granulocyte transfusions | Donor events | Recipient events |
Alavi 1977 | 12 | Not reported | 2 participants developed urticaria 28/176 (16%) transfusions associated with fever 12/176 (7%) of transfusions associated with chills but no fever |
Herzig 1977 | 15 | Not reported | < 10/68 (15%) obtained by continuous flow centrifugation > 96/129 (75%) obtained by leukapheresis were associated with transfusion reactions (fevers or chills) |
Higby 1975 | 17 | 14/67 faintness 1/67 chills 4/67 nausea 2/67 fainted 1/67 arm pain |
40/68 transfusions associated with fever |
Price 2015 | 56 | Not reported | 41% of participants had mild to moderate reactions (grade 1 to 2) ‐ fever, chills or changes in blood pressure 9 more severe reactions (grade 3 to 4), 6 hypoxia, 1 tachycardia, 1 hypotension, 1 allergic reactions |
Vogler 1977 | 32 | 2 chills 3 periorbital tingling 3 faintness 2 headache |
No dyspnoea No febrile reactions |
Winston 1982a | 48 | Not reported | 19 participants, 12 had fever and chills; 2 had fever, chills and a rash; 1 rash only; 4 dyspnoea |