Comparison 2. Sub group analyses for studies transfusing < and ≥ 1 x 10¹⁰ granulocytes per transfusion.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall mortality (up to 30 days)	6		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1 granulocytes < 1 x 1010	2	119	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.46, 2.24]
1.2 granulocytes ≥1 x 1010	4	202	Risk Ratio (M‐H, Fixed, 95% CI)	0.70 [0.49, 0.99]
2 Clinical response and reversal of infection	5		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 granulocytes < 1 x 1010	1	95	Risk Ratio (M‐H, Fixed, 95% CI)	0.86 [0.65, 1.14]
2.2 granulocytes ≥ 1 x 1010	4	191	Risk Ratio (M‐H, Fixed, 95% CI)	1.07 [0.82, 1.39]