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. 2016 Jul 1;11(7):e0158068. doi: 10.1371/journal.pone.0158068

Table 2. Single regression analyses with serum soluble (pro)renin receptor levels.

r P r P
Background factors Calcium 0.024 N.S.
    Age 0.101 N.S. Inorganic phosphorus 0.163 < 0.01
    Duration of hemodialysis therapy 0.031 N.S. Intact parathyroid hormone 0.117 N.S.
    Smoking history 0.087 N.S. Uric acid 0.081 N.S.
    Past history of cardiovascular diseases PRA 0.023 N.S.
        myocardial infarction -0.01 N.S. PAC 0.022 N.S.
        stroke -0.019 N.S. hANP 0.081 N.S.
peripheral artery disease -0.106 N.S. BNP 0.053 N.S.
    Body mass index 0.072 N.S. Physical function tests
    Systolic blood pressure during dialysis Echocardiography
at start -0.191 < 0.01 LVEF -0.051 N.S.
        highest value -0.186 < 0.01 LVMI -0.074 N.S.
        lowest value -0.182 < 0.01 IVC -0.100 N.S.
        difference between highest and lowest values -0.006 N.S. LADs -0.023 N.S.
        at end -0.189 < 0.01 E/e' -0.042 N.S.
    CTR 0.139 < 0.05 Carotid ultrasound examination
    Kt/V 0.079 N.S. max carotid IMT 0.003 N.S.
Blood tests ABI
    Hemoglobin 0.133 < 0.05 lower value -0.069 N.S.
    Hemoglobin A1c -0.081 N.S. average value -0.072 N.S.
    Creatinine -0.081 N.S. baPWV
    LDL cholesterol 0.048 N.S. higher value 0.080 N.S.
    HDL cholesterol -0.072 N.S. average value 0.077 N.S.
    Triglyceride 0.266 < 0.01 Abdominal CT
    Albumin -0.072 N.S. Visceral fat area 0.184 < 0.01
    CRP 0.170 < 0.01 Subcutaneous fat area 0.169 < 0.01
    Log CRP 0.267 < 0.001 Abdominal circumference 0.111 N.S.

CTR: cardiothoracic ratio, CRP: C-reactive protein, PRA: plasma renin activity, PAC: plasma aldosterone concentration, hANP: human atrial natriuretic peptide, BNP: brain natriuretic peptide, LVEF: left ventricular ejection fraction, LVMI: left ventricular mass index, IVC: inferior vena cava, LADs: left atrial internal dimension in systole, E/e': E over e-prime, IMT: intima-media thickness, ABI: ankle-brachial index, baPWV: brachial-ankle pulse wave velocity