Table 2. Laboratory and microbiological characteristics in 241 patients hospitalized for CAP, including stratification for vitamin D status.
| Variable | All patients (n = 241) | Vitamin D <30 nmol/L (n = 87) | Vitamin D 30–49 nmol/L (n = 81) | Vitamin D ≥50 nmol/L (n = 73) | Pa |
|---|---|---|---|---|---|
| Laboratory and radiographic findings | |||||
| Bilateral infiltrate, n (%) | 58 (24.1) | 17 (19.5) | 17 (21.0) | 24 (32.9) | .106 |
| Leucocyte count (×109/L) | 12.2 (9.3–16.6) | 13.2 (10.2–17.5) | 12.2 (8.5–16.3) | 11.0 (9.2–16.4) | .173 |
| CRP (mg/L) | 219 (101) | 214 (91) | 227 (114) | 216 (97) | .669 |
| Creatinine (μmol/L) | 76 (62–97) | 73 (62–94) | 78 (64–104) | 76 (65–96) | .232 |
| Albumin (g/L) | 28 (5) | 28 (5) | 28 (5) | 27 (5) | .055 |
| Etiology of CAP, n (%) | |||||
| By category of agents | .628 | ||||
| Pure Bacterial | 70 (29.0) | 23 (26.4) | 25 (30.9) | 22 (30.1) | |
| Pure Viral | 37 (15.4) | 11 (12.6) | 16 (19.8) | 10 (13.7) | |
| Viral–bacterial | 46 (19.1) | 21 (24.1) | 11 (13.6) | 14 (19.2) | |
| Unknown | 88 (36.5) | 32 (36.8) | 29 (35.8) | 27 (37.0) | |
| Streptococcus pneumoniae | 73 (30.3) | 30 (34.5) | 24 (29.6) | 19 (26.0) | .504 |
| Influenza viruses | 38 (15.8) | 15 (17.2) | 17 (21.0) | 6 (8.2) | .085 |
| Bacteraemia | 23 (9.5) | 8 (9.2) | 12 (14.8) | 3 (4.1) | .077 |
Data are mean (SD), median (25th–75th percentile) or No. (%). Abbreviations: CAP, community-acquired pneumonia; Vitamin D, 25-hydroxyvitamin D; CRP, C-reactive protein.
a Comparison between the three 25-hydroxyvitamin D categories.