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. 2016 Jul 1;24(4):347–362. doi: 10.4062/biomolther.2016.067

Table 6.

Examples of immunosuppressive compounds

Compounds Chemistry Species/ order Mode of action References
Simplexides Glycolopids Plakortis simplex/Homosclerophorida Inhibitors of T cell proliferation Costantino et al., 1999
Polyoxygenated sterols Sterol Dysidea sp./Dendroceratida IL 8 inhibitor de Almeida Leone et al., 2000
Contignasterol Oxygenated sterol Petrosia contignata/Haplosclerida Histamine release inhibitor Takei et al., 1994
Pateamine A Thiazole macrolide Mycale sp./Poecilosclerida IL-2 inhibitor Northcote et al., 1991
Iso-iantheran A Polyketide Ianthella quadrangulata Ionotropic P2Y11 receptor activation Greve et al., 2007