Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 1;24(4):410–417. doi: 10.4062/biomolther.2015.153

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2016, The Korean Society of Applied Pharmacology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 3. — Concentration-dependent effects of quercetin and its glycosides on I_ACh. (A) The representative trace of quercetin- or quercetin gly-coside- (30 μM each) mediated effects on I_ACh. I_ACh in oocytes expressing the α7 nAChR was elicited at a holding potential of −80 mV for 30 s in the presence of 200 μM ACh. Quercetin and its glycosides were pre-applied 30 s before ACh application. (B) The representative trace of quercetin- and quercetin glycoside- (300 μM each) mediated effects on I_ACh. I_ACh in oocytes expressing the α7 nAChRs was elicited at a holding potential of −80 mV for 30 s in the presence of 200 μM ACh. Quercetin and its glycosides were pre-applied 30 s before ACh application. Traces represent six separate oocytes from three different batches of frogs. (C–D) Concentration-dependent effects of quercetin and quercetin glycosides on I_ACh. The solid lines were fit using the Hill equation. Each point represents the mean ± S.E.M. (n=9–12/group).