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. 2016 Jul 1;24(4):433–437. doi: 10.4062/biomolther.2015.184

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Copyright ©2016, The Korean Society of Applied Pharmacology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2. — SM rescues ethanol-induced decrease of fEPSPNMDAR. To isolate fEPSPNMDAR, NBQX (50 μM) was perfused during recording. The peak of the evoked field potential responses were averaged from four consecutive recordings (EPSPs) evoked at 30 s intervals (Ampk). (A) The effect of SM on fEPSPNMDAR. (B) SM reduced ethanol-induced decrease of fEPSPNMDAR in a concentration dependent manner. Data were normalized to baseline (0–20 min) and represent mean ± S.E.M. EtOH, ethanol. SM, Salvia miltiorrhiza extract.