Table 2.

Anxiety, Depression, and Bowel Symptom Change from Baseline to Endpoint of Study

	Baseline	1st course	2nd course	3rd course	F		Pb
SAS					G	4.404	0.039
Experiment group (n = 38)	55.26 ± 5.83	52.11 ± 5.48	46.42 ± 3.94	41.82 ± 5.31	T	101.361	< 0.001
Control group (n = 36)	55.78 ± 5.46	50.94 ± 4.71	49.00 ± 3.84	46.75 ± 3.71	G*T	10.549	< 0.001
Pa	0.697	0.333	0.006	< 0.001
SDS					G	4.813	0.031
Experiment group (n = 38)	58.16 ± 7.58	53.03 ± 5.19	47.08 ± 3.93	43.08 ± 4.00	T	120.737	< 0.001
Control group (n = 36)	57.81 ± 5.92	52.64 ± 4.67	50.11 ± 4.28	48.75 ± 5.72	G*T	9.338	< 0.001
Pa	0.825	0.737	0.002	< 0.001
WCS					G	13.131	0.001
Experiment group (n = 38)	15.29 ± 3.42	15.08 ± 2.66	12.00 ± 2.72	10.03 ± 1.98	T	85.376	< 0.001
Control group (n = 36)	16.61 ± 4.07	16.58 ± 3.29	14.94 ± 2.69	12.64 ± 3.04	G*T	2.869	0.043
Pa	0.134	0.033	< 0.001	< 0.001

^aStudent’s t test.

^bANOVA repeated measures test.

SAS, self-rating anxiety scale; SDS, self-rating depression scale; WCS, Wexner constipation score; G, treatment effect; T, time effect; G*T, interaction between time and treatment.

Data are presented as mean ± SD.