Table 3. Cox proportional hazards model for time-to-hospital-mortality in cohorts of patients with bloodstream infection (n=90) and their controls (n=223).
BSI: bloodstream infection. IQR, interquartile range.
| Univariable analysis | Multivariable model | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | aHR | 95% CI | p | |
| BSI vs. colonization | 2.71 | 1.60–4.65 | <0.001 | 2.59 | 1.52–4.50 | <0.001 |
| Age, median (IQR)* | 1.00 | 0.99–1.02 | 0.72 | |||
| Female | 1.18 | 0.69–2.06 | 0.55 | |||
| Race/Ethnicity | 0.02 | 0.19 | ||||
| White (ref.) | - | - | - | - | ||
| Black | 2.02 | 1.19–3.44 | 1.65 | 0.95–2.87 | ||
| Hispanic or Other# | 0.62 | 0.03–2.92 | 0.82 | 0.05–3.98 | ||
| Charlson comorbidity index, median (IQR) | 1.10 | 1.00–1.21 | 0.05 | 1.09 | 0.99–1.20 | 0.09 |
| Diabetes mellitus | 0.77 | 0.45–1.30 | 0.33 | |||
| Renal failure‡ | 1.95 | 1.14–3.29 | 0.02 | |||
| Heart disease | 1.04 | 0.61–1.76 | 0.90 | |||
| COPD | 1.09 | 0.58–1.93 | 0.78 | |||
| Malignancy | 1.54 | 0.84–2.69 | 0.16 | |||
‡
renal failure defined as creatinine >2 mg/dL upon admission.
#
Grouped given small numbers in the “Other” and “Hispanic” race categories.
*
Analyzed per year increase.