Table 4. Cox proportional hazards model for time-to-hospital-mortality in cohorts of patients with pneumonia (n=49) and their controls (n=260).
RTI: respiratory tract infection. IQR, interquartile range.
| Univariable analysis | Multivariable model | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | aHR | 95% CI | p | |
| pneumonia vs. colonization | 2.48 | 1.31–4.58 | <0.01 | 3.44 | 1.80–6.48 | <0.001 |
| Age, median (IQR)* | 1.02 | 1.00–1.05 | 0.07 | 1.02 | 0.99–1.04 | 0.12 |
| Female | 1.34 | 0.71–2.67 | 0.37 | |||
| Race/Ethnicity | 0.03 | 0.04 | ||||
| White (ref.) | - | - | - | - | ||
| Black | 1.97 | 1.05–3.65 | 1.65 | 0.87–3.10 | ||
| Hispanic or Other# | 0.39 | 0.02–1.87 | 0.25 | 0.01–1.23 | ||
| Charlson comorbidity index, median (IQR) | 1.18 | 1.05–1.31 | <0.01 | 1.19 | 1.06–1.34 | <0.01 |
| Diabetes mellitus | 1.41 | 0.76–2.69 | 0.27 | |||
| Renal failure‡ | 2.21 | 1.16–4.09 | 0.02 | |||
| Heart disease | 1.36 | 0.73–2.68 | 0.33 | |||
| COPD | 1.17 | 0.60–2.20 | 0.63 | |||
| Malignancy | 1.10 | 0.47–2.25 | 0.82 | |||
‡
renal failure defined as creatinine >2 mg/dL upon admission.
#
Grouped given small numbers in the “Other” and “Hispanic” race categories.
*
Analyzed per year increase.