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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2016 May 27;25(7):820–826. doi: 10.1002/pds.4044

Table 3.

Predictive values of the algorithms

Algorithm Records Identified Flare cases Documentation of gout
n n PPV% (95% CI) n PPV% (95% CI)
Medication

 ICD-9 + medication claim for any gout-related medications* 503 268 53.3 (48.9, 57.7) 498 99.0 (98.1, 99.9))

 ICD-9 + medication claim for colchicine 302 163 54.0 (48.4, 59.6) 300 99.3 (98.3, 100)

 ICD-9 + medication claim for NSAID/cox-2 selective inhibitor 174 87 50.0 (42.6, 57.4) 173 99.4 (98.3, 100)

 ICD-9 + medication claim for glucocorticoids 270 145 53.7 (47.8, 59.7) 266 98.5 (97.0, 100)

Outpatient

 ICD-9 + medication claim for any gout-related medications* 75 42 56.0 (44.8, 67.2) 74 99.0 (96.8, 100))

Procedure

 ICD-9 + CPT or J code within 7 days 290 172 59.3 (53.7, 65.0) 287 99.0 (97.9, 100)

 ICD-9 + CPT or J code on same day 196 134 68.4 (61.9, 74.9) 194 99.0 (97.6, 100)

Negative Predictive
Records Identified Flare cases Documentation of gout
n n NPV % (95% CI) n PPV% (95% CI)

 ICD-9 + NO medication claim for any gout-related medications* 200 29 85.2 (80.2, 90.2) 196 98.0 (96.1, 100)

95% CI= 95% confidence interval, ICD-9=International Classification of Diseases, 9th Revision; CPT= Current Procedural Terminology; PPV= Positive Predictive Value.

*

gout-related medications include colchicine, NSAIDs, cox-2 selective inhibitor, and glucocorticoids.