Table 1.
Characteristics of subjects, overall and by baseline estradiol concentration tertiles.
| Variable | Overall (SD) | Estradiol tertiles (pmol/L) | p-Value | ||
|---|---|---|---|---|---|
| Lowest | Middle | Highest | |||
| Estradiol (pmol/L) | 81.20 (25.95) | 31.06—66.37 | 66.38—90.01 | 90.02—182.45 | |
| Age (years) | 51.85 (11.50) | 47.97 | 52.24 | 55.40 | <0.001 |
| Intra-abdominal fat area at baseline (cm2) | 96 (51.88) | 97.70 | 91.51 | 98.83 | 0.66 |
| 5 year change in intra-abdominal fat area (cm2) | 11.44 (35.46) | 11.40 | 11.99 | 10.91 | 0.99 |
| 10 year change in intra-abdominal fat area (cm2) | 19.41 (39.77) | 20.69 | 16.61 | 20.96 | 0.77 |
| Subcutaneous fat area at baseline (cm2) | 140.53 (68.27) | 149.62 | 135.63 | 136.29 | 0.38 |
| 5 year change in subcutaneous fat area (cm2) | 14.63 (29.98) | 20.61 | 10.23 | 12.69 | 0.10 |
| 10 year change in subcutaneous fat area (cm2) | 22.24 (40.43) | 30.58 | 16.80 | 19.30 | 0.09 |
| Weight at baseline (kg) | 71.31 (10.09) | 73.62 | 69.62 | 70.68 | 0.05 |
| 5 year change in weight (kg) | 0.89 (3.34) | 1.47 | 0.89 | 0.27 | 0.10 |
| 10 year change in weight (kg) | 1.89 (4.71) | 2.63 | 1.44 | 1.61 | 0.26 |
| BMI at baseline (kg/m2) | 25.37 (3.10) | 25.92 | 24.88 | 25.30 | 0.13 |
| Fasting plasma glucose at baseline (mmol/L) | 5.33 (0.64) | 5.22 | 5.33 | 5.43 | 0.12 |
SD: standard deviation; BMI: body mass index.