Table 3.

Multiple linear regression analysis of the change in intra-abdominal fat area over (a) 5 years and (b) 10 years by baseline estradiol level with adjustment for baseline age, baseline intra-abdominal fat, and the change in weight over time.

	β coefficient	95% confidence interval	p-Value
(a) Multiple linear regression analysis of the change in intra-abdominal fat area over 5 years
Age (years)	0.88	(0.45, 1.30)	<0.01
Intra-abdominal fat area at baseline (cm2)	−0.22	(−0.31, −0.14)	<0.01
Estradiol at baseline (pmol/L)	−0.05	(−0.22, 0.11)	0.52
5 year change in weight (kg)	5.37	(4.03, 6.71)	<0.01
(b) Multiple linear regression analysis of the change in intra-abdominal fat area over 10 years
Age (years)	0.55	(0.09, 1.01)	0.02
Intra-abdominal fat area at baseline (cm2)	−0.16	(−0.25, −0.07)	<0.01
Estradiol at baseline (pmol/L)	−0.05	(−0.23, 0.12)	0.55
10 year change in weight (kg)	4.94	(3.92, 5.97)	<0.01