Table 1.
Baseline Characteristics by Medication Condition, Mean (SD) or n (%)
| Placebo (n=17) | 1 mg/day Varenicline (n=12) | 2 mg/day Varenicline (n=15) | p | |
|---|---|---|---|---|
|
| ||||
| Age | 35.3 (9.47) | 33.9 (7.29) | 34.4 (12.6) | 0.93 |
| Sex (% male) | 65% | 58% | 73% | 0.71 |
| Race (% White) | 0.15 | |||
| White | 8 (47) | 8 (67) | 12 (80) | |
| Other | 9 (53) | 4 (33) | 3 (20) | |
| Education | 0.03 | |||
| ≤ High school | 8 (47) | 5 (42) | 1 (7) | |
| ≥ College | 9 (53) | 7 (58) | 14 (93) | |
| Marital Status | 0.09 | |||
| Not married | 13 (76) | 9 (75) | 15 (100) | |
| Married | 4 (24) | 3 (25) | 0 (0) | |
| Tobacco Use (smokers only) | ||||
| Cigarettes per day | 13.9 (7.26) | 13.5 (4.08) | 15.9 (6.39) | 0.68 |
| FTND scorea* | 4.30 (2.31) | 4.63 (1.85) | 4.0 (1.94) | 0.82 |
| Alcohol Use | ||||
| Weekly frequency (days)b | 4.94 (1.74) | 4.14 (1.60) | 4.39 (1.55) | 0.40 |
| Drinks per episode | 6.66 (3.46) | 6.66 (2.75) | 6.19 (3.26) | 0.90 |
| AUDIT scoresc | 13.5 (6.97) | 12.3 (4.58) | 10.1 (3.61) | 0.21 |
AUDIT, Alcohol Use Disorders Identification Test; FTND, Fagerström Test for Nicotine Dependence
a
Range: scores ≥ 4 for nicotine dependence.
b
Means calculated over 30 days before intake.
c
Scores ≥ 8 for alcohol misuse.
*
n=10, 8, 9 for placebo, 1 mg/day varenicline, and 2 mg/day varenicline, respectively.
Note: education (p=.03); otherwise, no difference between groups using chi-square or ANOVA where appropriate.