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(a) Cross-section view of the nanoslit device. (b) Top-view of the lateral constriction used to initiate ICP in the nanoslit (biomarkers shown as green particles). (c) Alteration of electrokinetic trapping potential profile due to ICP enables exponential enhancement in biomarker numbers. The H-shaped ICP device from prior work: (d) top-view (e) cross-section. (f) Comparison of calculated surface to total ion current away from the perm-selective interface for the different geometries.
