Table 5.
Effect of Solenostemon monostachyus extract on formalin–induced hind paw licking in mice
|
Treatment/
Dose (mg/kg) |
Time intervals (mins)
|
||||||
|---|---|---|---|---|---|---|---|
| 5 | 10 | 15 | 20 | 25 | 30 | Total | |
| Control | 14.00 1.15 | 8.02 1.00 | 8.33 0.57 | 8.00 0.57 | 9.00 0.87 | 14.00 2.08 | 61.35 6.24 |
|
Extract
75 |
9.00 0.01 | 2.66 0.33*** | 2.66 0.31*** | 2.66 0.58*** | 1.66 0.67*** | 0.00 0.00*** | 18.64 1.90*** |
| 150 | 14.64 1.40 | 0.00 0.00*** | 0.00 0.00*** | 0.66 0.66*** | 2.00 0.16*** | 1.33 0.33*** | 18.63 2.55*** |
| 225 | 6.66 0.66 | 0.00 0.00*** | 1.33 0.00*** | 0.33 0.33*** | 3.33 0.32*** | 0.66 0.66*** | 12.31 1.97*** |
| ASA 100 | 7.66 0.51 | 3.00 0.00*** | 2.33 0.85*** | 2.66 0.45*** | 3.33 0.66*** | 3.00 0.37*** | 21.98 2.84*** |
Data are expressed as mean SEM. Significant at
***
p < 0.001. When compared to control ,n = 6.