Table 1.

Summary of all identified proteins from proteomics profiling

Protein category	Quantified peptides	P-value (ANOVA)	Number of proteins	Ratio between conditions
1	>2	<0.05	104	>1.5 fold
2	1	<0.05	98	>1.5 fold
3	>1	<0.05	229	<1.5 fold
4	>1	>0.05	896	Not applicable

Proteins identified were divided into 4 categories based on the quantity of peptides, ratio between conditions and p-value. Differential expression of proteins between LPON and the untreated cells was considered as significant if fold-change was ≥1.5, quantified with at least two peptides and p-value <0.05 (Category 1)