Table 2.

Antibody binding of 47 AQP4-IgG-positive baseline serum samples to AQP4-M23, AQP4-M1 and AQP4-M23 mutants

	AQP4-IgG binding ratio (mean, 95 % CI)	AQP4-IgG binding in % of AQP4-M23 (mean, 95 % CI)
AQP4-M23 isoform	4.84 (3.98–5.70)	Reference (100 %)
AQP4-M1 isoform	1.48 (1.11–1.86)	25.83 (20.19–31.47)
AQP4-mycA (loop A)	2.74 (2.17–3.31)	38.15 (28.95–47.35)
AQP4-delA3 (loop A)	2.85 (2.26–3.44)	40.91 (31.99–49.82)
AQP4-mycC (loop C)	1.49 (1.38–1.60)	13.12 (9.34–16.90)
AQP4-N153Q (loop C)	3.88 (3.26–4.50)	67.35 (56.88–77.81)
AQP4-mycE (loop E)	1.17 (1.12–1.23)	5.39 (3.69–7.08)
AQP4-H230G (loop E)	2.69 (2.12–3.25)	36.28 (29.62–42.95)