Table 2.

Transmission disequilibrium test for individual GNAL polymorphisms

SNP	Allele	Freq.	Transmissions		TDT(all)		TDT(one sib)		PDT
			T	NT	χ2	P	χ2	P	Z	P
rs8087266 G/A	G	0.70	90	70	2.507	0.113	2.355	0.125	1.787	0.074
rs1005270 T/C	T	0.83	77	67	0.695	0.405	1.526	0.217	0.953	0.341
rs8095592 G/A	G	0.70	98	87	0.654	0.419	0.530	0.467	0.550	0.583
rs2052661 G/C	G	0.71	96	81	1.273	0.259	0.961	0.327	0.999	0.318
rs2161961 A/G	A	0.75	101	68	6.485	0.011*	7.796	0.005*	2.494	0.013*
rs8098539 A/G	A	0.64	107	83	3.040	0.081	2.538	0.111	1.665	0.096
rs9962277 C/T	C	0.79	73	64	0.592	0.442	1.072	0.300	0.752	0.452
rs2276134 T/C	T	0.85	55	54	0.009	0.924	0.045	0.831	−0.157	0.876
rs1786581 C/T	C	0.83	71	61	0.758	0.384	0.154	0.695	1.021	0.307
rs787554 C/T	C	0.78	72	88	1.603	0.206	0.954	0.329	−1.265	0.206
rs787558 T/C	T	0.73	93	81	0.828	0.363	1.363	0.243	1.025	0.305
rs3892113 T/G	T	0.92	32	29	0.148	0.701	0.308	0.579	0.000	1.000

^*P value after 1000 permutations : P_TDT(all) = 0.101; P_{TDT(one sib)} = 0.071; P_PDT = 0.101.