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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2016 May 17;25(7):1037–1042. doi: 10.1158/1055-9965.EPI-15-1221

Figure 3. Study A: Presence, sensitivity and specificity of CAMLs in patients with known invasive breast cancer versus healthy control volunteers.

Figure 3

(A) CAMLs were found in 38 of 41 patients with known invasive breast cancer, but in none of the 16 healthy controls. (B) The number of CAMLs ranged 0–105 per 7.5 mL blood sample in patients with cancer. (C) ROC curve shows a clear stratification between a healthy control population from a malignant population, AUC=0.96. Sensitivity: 93% (CI95% 80–99%) Specificity: 100% (CI95% 79–100%) PPV: 100% (CI95% 91–100%) NPV: 84% (CI95% 60–97%).