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Transient drug-induced synaptic plasticity mechanisms of cortico-accumbens glutamatergic synapses that are shared during the execution of drug seeking behaviors.
| AMPA Receptor Function |
Spine Head Diameter |
MMP-9 Activity | Refs | |
|---|---|---|---|---|
| Alcohol | ↑ | No data | No data | [114, 115] |
| Cocaine | ↑ | ↑ | ↑ | [30, 69, 72, 74, 99, 116] |
| Nicotine | ↑ | ↑ | ↑ | [28, 99] |
| Heroin | ↑ * | ↑ | ↑ | [84, 99] |
measured as field EPSPs
