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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Neurobiol Dis. 2016 May 1;93:226–242. doi: 10.1016/j.nbd.2016.04.010

Figure 7. Thrombin and neurosin increase astrocyte STAT3 signaling in a PAR1-dependent manner.

Figure 7

Treatment of astrocytes with (A) thrombin or (C) neurosin (150 ng/ml) for 24 h resulted in a significant increase in pSTAT3 in PAR1+/+, but not PAR1−/− astrocytes (B and D show corresponding signal for total STAT3 in each case). (*P < 0.05, Students t-test).