Table 3.
Tissue biomarker expressiona.
| Baseline (% positive) | Post-Intervention (% positive) | p valued | |
|---|---|---|---|
| 8OHdG (n = 25) | 39.9 (39.1)b,c | 34.9 (30.7) | 0.52 |
| Ki67 (n = 29) | 35.9 (14.0)e | 36.9 (18.3) | 0.44 |
| CC3 (n = 27) | 1.62 (2.86)e | 1.00 (2.11) | 0.25 |
a
longitudinally sectioned crypts opening to the lumen were selected for scoring. Slides with fewer than 500 total nuclei in the selected regions were excluded for the statistical analysis. The marker expression from different segments was averaged for participants with tissue sections from multiple esophageal segments.
b
median (interquartile range)
c
% of strongly and moderately stained nuclei
d
derived from signed rank test
e
% of positively stained nuclei
Abbreviations: 8OHdG: 8-hydroxydeoxyguanosine; CC3: cleaved caspase 3