Table 4.
Comparison of non-infectious complications of blood transfusion reported in studies from North India
| Current study, Delhi (Jan 2011–Dec 2013) | AIIMS, Delhi Study [5] (Dec 2007–April 2012) | PGIMER, Chandigarh Study [6] (July 2002–July 2003) | Multi- superspeciality hospital, North, Delhib Jan 2012–Dec 2013 | |
|---|---|---|---|---|
| Units transfused | 18,914 | 380,658 | 56,503 | 8487 |
| Patients transfused | 5785 | NA | 29,720 | 2803 |
| RBC used | 4 log leukodepleted | Non-leukodepleted to leukodepleteda | Non-leukodepleted | Leukoreduced using buffy coat method |
| Alloantibody antibody screening done | Yes | No | No | Yes |
| Hemovigilance | Active feedback | Passive reporting | Passive reporting | Passive reporting |
| Number of total reactions | 61 | 196 | 105 | 12 |
| Reactions within 24 h of transfusion (% of total reactions) | 61 (100) | 195 (99.5) | 102 (97.1) | 12 (100) |
| Mortality due to acute transfusion reactions | 0 | NA | 7 (p = 0.04) | 0 |
| Non-immune hemolysis (% of total reactions) | 0 (0) | 5 (2.6) p = 0.21 |
6 (5.7) p = 0.06 |
0 (0) |
| Incidence of adverse reaction per unit transfused (%) | 0.32 | 0.05 p < 0.0001 |
0.19 p = 0.0005 |
0.14 p = 0.007 |
| Incidence of adverse reaction per patient transfused (%) | 1.00c | NA | 0.35 p < 0.0001 |
0.43 p = 0.005 |
NA data not available
aNon-leukodepleted from 2007 to 2009; 2010–2012—leukofiltered; personal communication
bPersonal communication
c61 reactions were seen in 58 different patients