Fig. 1.

The follicular fluid concentrations of sRAGE, VEGF, TNF-α, IL-6, and CRP in the PCOS and the control groups. a sRAGE concentrations in the follicular fluid were measured with ELISA. The sRAGE concentrations in the follicular fluid were lower in the PCOS group than in the controls (666.753 ± 233.153 vs. 1518.608 ± 872.130; P = 0.000). b VEGF, TNF-α, IL-6, and CRP levels in the follicular fluid were measured with ELISA. VEGF, TNF-α, IL-6, and CRP concentrations in the follicular fluid were higher in the PCOS group than in the controls (155.761 ± 23.314 vs. 110.955 ± 21.838, 42.636 ± 7.726 vs. 21.136 ± 9.266, 29.932 ± 5.148 vs. 17.327 ± 6.495, and 9.249 ± 1.385 vs. 5.839 ± 1.382, respectively; P < 0.05). sRAGE soluble isoform of the receptor for advanced glycation endproducts, VEGF vascular endothelial growth factor, TNF-α tumor necrosis factor α, IL-6 interleukelin-6, and CRP C-reactive protein