Table 1.
Components of Chinese drug decoction pieces in the CQCQD formula and their production lot numbers and the relative contents of major active ingredients.
| Pharmaceutical name and Chinese phonetic name | Botanical name and plant part | Composition (%) | Lot number | Quantitative analysis of major active ingredients | |
|---|---|---|---|---|---|
| Reference markers (HPLC) | Relative content (% w/w) | ||||
| Bupleuri Radix (Chai Hu) | Bupleurum chinense DC (Apiaceae), root | 11.111 | 2014100802 | Saikosaponin a | 0.383–0.421 |
| Saikosaponin d | 0.381–0.398 | ||||
|
| |||||
| Scutellariae Radix (Huang Qin) | Scutellaria baicalensis Georgi (Lamiaceae), root | 11.111 | 2014081003 | Baicalin | 12.338–14.321 |
|
| |||||
| Rhei Radix et Rhizoma (Da Huang) | Rheum palmatum L. (Polygonaceae) | 14.814 | 2014080301 | Aloe-emodin | 0.348–0.367 |
| Rhein | 1.002–1.162 | ||||
| Emodin | 0.513–0.628 | ||||
| Chrysophanol | 0.661–0.702 | ||||
| Physcion | 0.268–0.301 | ||||
|
| |||||
| Natrii Sulfas (Mang Xiao) | Mirabilite (sulfate minerals), crystal | 14.814 | 2014030506 | Thenardite | 99.812–99.993 |
|
| |||||
| Magnoliae Officinalis Cortex (Hou Pu) | Magnolia officinalis Rehder & E. H. Wilson (Magnoliaceae), root, branch, and stem bark | 11.111 | 2014060501 | Magnolol | 2.118–2.491 |
| Honokiol | 2.181–2.228 | ||||
|
| |||||
| Aurantii Fructus Immaturus (Zhi Shi) | Citrus aurantium L. (Rutaceae), immature fruit | 11.111 | 2014053101 | Synephrine | 0.612–0.641 |
| Hesperidin | 1.231–1.445 | ||||
|
| |||||
| Artemisiae Scopariae Herba (Yin Chen) | Artemisia scoparia Waldst. & Kitam. (Asteraceae), aerial part | 11.111 | 2014030601 | Chlorogenic acid | 0.598–0.693 |
| Escoparone | 0.598–0.6341 | ||||
|
| |||||
| Gardeniae Fructus (Zhi Zi) |
Gardenia jasminoides
J. Ellis (Rubiaceae), ripe fruit |
14.814 | 2014110301 | Geniposide | 5.989–6.959 |