Table 1.
Treatment | Dose (mg/kg) | N | Time analysis (hours) | MN-PCE/1,000 cells∧ (mean ± SD) | ANOVA |
---|---|---|---|---|---|
Control (water) | 0 | 5 | 0 | 0.5 ± 0.3 | |
24 | 0.8 ± 0.2 | ||||
48 | 0.9 ± 0.4 | ||||
72 | 1.2 ± 0.2 | ||||
| |||||
Control (corn oil) | 0 | 5 | 0 | 0.2 ± 0.2 | |
24 | 0.3 ± 0.3 | ||||
48 | 0.4 ± 0.4 | ||||
72 | 0.3 ± 0.3 | ||||
| |||||
AA∗ | 100 | 5 | 0 | 0.5 ± 0.3 | |
24 | 0.2 ± 0.2 | ||||
48 | 0.3 ± 0.2 | ||||
72 | 0.3 ± 0.4 | ||||
| |||||
α-TOH∗ | 20 | 5 | 0 | 0.3 ± 0.4 | |
24 | 0.5 ± 0.3 | ||||
48 | 0.3 ± 0.2 | ||||
72 | 0.3 ± 0.2 | ||||
| |||||
V2O5 | 40 | 5 | 0 | 1.4 ± 0.4 | |
24 | 2.2 ± 0.2 | a, c, d | |||
48 | 3.0 ± 0.6 | a, b, c, d | |||
72 | 3.9 ± 0.8 | a, b, c, d | |||
| |||||
AA + V2O5 | 100 + 40 | 5 | 0 | 1.1 ± 0.2 | |
24 | 0.9 ± 0.4 | ||||
48 | 0.7 ± 0.2 | ||||
72 | 0.8 ± 0.4 | ||||
| |||||
α-TOH + V2O5 | 20 + 40 | 5 | 0 | 0.7 ± 0.4 | |
24 | 1.0 ± 0.3 | ||||
48 | 1.2 ± 0.2 | ||||
72 | 0.8 ± 0.2 |
a p < 0.05 versus controls; b p < 0.05 versus V2O5 0 h; c p < 0.05 versus AA + V2O5; d p < 0.05 versus α-TOH + V2O5.
∗AA: vehicle water, distilled; α-TOH: vehicle corn oil.
∧2,000 PCE were evaluated in each mouse (5 mice per group).