Table 2.
Averages of the PCE/NCE ratio in peripheral blood of mice.
Treatment | Dose (mg/kg) | N | Time analysis (hours) | PCE/NCE 1,000 cells∧ (mean ± SD) | ANOVA |
---|---|---|---|---|---|
Control (water) | 0 | 5 | 0 | 127.4 ± 5.9 | |
24 | 123.2 ± 11.2 | ||||
48 | 133.6 ± 10.1 | ||||
72 | 128.8 ± 4.9 | ||||
| |||||
Control (corn oil) | 0 | 5 | 0 | 115.0 ± 3.9 | |
24 | 115.5 ± 4.0 | ||||
48 | 111.7 ± 3.4 | ||||
72 | 114.0 ± 2.2 | ||||
| |||||
AA∗ | 100 | 5 | 0 | 100.6 ± 2.0 | |
24 | 68.8 ± 1.9 | a, b | |||
48 | 67.2 ± 3.0 | a, b | |||
72 | 68.2 ± 0.8 | a, b | |||
| |||||
α-TOH∗ | 20 | 5 | 0 | 103.4 ± 3.6 | |
24 | 75.4 ± 3.4 | a, c | |||
48 | 66.2 ± 7.0 | a, c | |||
72 | 67.8 ± 2.4 | a, c | |||
| |||||
V2O5 | 40 | 5 | 0 | 123.8 ± 6.6 | |
24 | 125.4 ± 4.2 | d, f | |||
48 | 124.8 ± 4.3 | d, f | |||
72 | 136.6 ± 3.0 | d, f | |||
| |||||
AA + V2O5 | 100 + 40 | 5 | 0 | 101.2 ± 4.7 | |
24 | 95.8 ± 5.3 | a | |||
48 | 88.4 ± 1.3 | a | |||
72 | 87.6 ± 1.9 | a | |||
| |||||
α-TOH + V2O5 | 20 + 40 | 5 | 0 | 116.0 ± 4.4 | |
24 | 87.0 ± 3.4 | a, e | |||
48 | 84.6 ± 3.4 | a, e | |||
72 | 87.4 ± 2.2 | a, e |
a p < 0.05 versus control; b p < 0.05 versus AA 0 h; c p < 0.05 versus α-TOH 0 h; d p < 0.05 versus AA + V2O5; e p < 0.05 versus AA + V2O5 0 h; f p < 0.05 versus α-TOH + V2O5.
∗AA: vehicle water, distilled; α-TOH: vehicle corn oil.
∧1,000 erythrocytes were evaluated in each mouse (5 mice per group).