Table 4.
The number of emetic responses by mink administered a fixed oral dose (0.5 mg/kg bw) of type A and type B trichothecenes. The 0.5 mg/kg oral dietary dose was the common dose included in all animal sub-studies conducted by Wu et al. (2012a) when investigating the emetic responses of mink to a range of doses of trichothecenes. The frequency of retching and vomiting were counted as discrete events. The total number of emetic events was calculated as the sum of retching and vomiting. Total emetic events recorded as Means ± SD. Different letters superscripted under “Total” indicates those groups are significantly different (p≤ 0.05).
| Type | Trichothecene | Number of emetic events | ||
|---|---|---|---|---|
| Retching | Vomiting | Total | ||
| A | HT-2 | 222 | 23 | 245 ± 32a |
| A | T-2 | 191 | 21 | 212 ± 53a |
| B | 3-ADON | 16 | 4 | 20 ± 9c |
| B | 15-ADON | 24 | 6 | 30 ± 5c |
| B | DON | 62 | 9 | 71 ± 10b |
| B | FX | 45 | 13 | 58 ± 4b |
| B | NIV | 55 | 9 | 64 ± 15b |
DON (deoxynivalenol), 3-ADON (3-acetyldeoxynivalenol), 15-ADON (15-acetyldeoxynivalenol), NIV (nivalenol), FX (Fusarenon X), HT-2 (HT-2 toxin), T-2 (T-2 toxin).