Table 5.

Puberty Measures, F₁ males and females^a,^b

Endpoint	Diet
	NIH-41	5K96	5001	AIN-93	SPC	SPC-IF
Males, breeder arm
n	20	20	20	19	19	20
Day of PPS, PND	29.4 ± 0.4	29.0 ± 0.3	29.6 ± 0.6	28.0 ± 0.4	29.3 ± 0.6	29.8 ± 0.5
Weight at PPS, g	26.0 ± 0.6	25.7 ± 0.7	24.5 ± 0.6	22.4 ± 0.8*	18.2 ± 0.9*	17.6 ± 0.8*
Males, glucose challenge arm
n	20	20	19	18	20	19
Day of PPS, PND	28.1 ± 0.3	27.8 ± 0.3	28.2 ± 0.2	28.1 ± 0.3	27.8 ± 0.4	29.5 ± 0.3*
Weight at PPS, g	24.0 ± 0.6	23.4 ± 0.6	23.5 ± 0.6	22.9 ± 0.6	16.0 ± 0.6*	16.3 ± 0.6*
Females, breeder arm
n	19	19	19	20	20	20
Day of VO, PND	25.0 ± 0.4	25.2 ± 0.5	25.8 ± 0.5	25.0 ± 0.3	26.9 ± 0.4*	25.0 ± 0.3
Weight at VO, g	16.6 ± 0.5	17.0 ±0.5	17.1 ± 0.4	17.9 ± 0.5	14.0 ± 0.4*	12.3 ± 0.5*
Time to first estrus, Median PND (95% CI)	32 (NA)	33 (32 – 33)	34 (34 – 36)*	30 (29 – 30)*	36 (NA)*	33 (33 – 34)*
Females, glucose challenge arm
n	20	20	20	20	20	20
Day of VO, PND	25.5 ± 0.4	25.5 ± 0.4	25.5 ± 0.4	24.7 ± 0.3	26.4 ± 0.4	24.7 ± 0.3
Weight at VO, g	17.9 ± 0.5	17.9 ± 0.5	17.1 ± 0.4	17.5 ± 0.5	14.0 ± 0.6*	12.2 ± 0.5*
Time to first estrus, Median PND (95% CI)	37 (35 – NA)	34 (33 – 36)	42 (42 – NA)*	40 (34 – NA)	42 (40 – 44)*	42 (38 – 43)*

^aNA, 95% confidence interval (CI) could not be calculated due to right censoring.

^bMean counts ± S.E.M., except time to first estrus.

Shaded cell indicates statistically significant difference from NIH-41 diet group ;

^*p < 0.05.