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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Food Chem Toxicol. 2016 May 24;94:39–56. doi: 10.1016/j.fct.2016.05.014

Table 6.

Adult F1 Male Organ Weights (Absolute, Relative to Brain Weight, and Relative to Terminal Body Weight)a

Organ Diet
NIH-41 5K96 5001 AIN-93 SPC SPC-IF
Body Weight (g) 45.80 ± 1.382 44.16 ± 1.267 (19) 41.18 ± 1.122 43.03 ± 1.441 41.06 ± 1.224* 38.50 ± 1.395**
Brain
Absolute (g) 0.542 ± 0.006 0.525 ± 0.007 0.525 ± 0.004 0.531 ± 0.005 0.520 ± 0.004* 0.507 ± 0.007***
Rel to Body (mg/g) 12.04 ± 0.375 12.05 ± 0.383 12.87 ± 0.282 12.57 ± 0.404 12.88 ± 0.383 13.46 ± 0.435**
Retroperitoneal Fat Pad
Absolute (g) 0.635 ± 0.062 0.641 ± 0.032 0.414 ± 0.041* 0.520 ± 0.083 0.501 ± 0.062 0.447 ± 0.052
Rel. to Brain (g/g) 1.169 ± 0.114 1.228 ± 0.067 0.785 ± 0.076 0.979 ± 0.157 0.961 ± 0.118 0.881 ± 0.105
Rel. to Body (mg/g) 13.45 ± 1.052 14.47 ± 0.607 9.781 ± 0.829 11.38 ± 1.481 11.66 ± 1.226 11.08 ± 0.919
Kidney
Absolute (g) 0.684 ± 0.022 (19) 0.665 ± 0.020 0.677 ± 0.023 0.606 ± 0.014* 0.521 ± 0.017*** 0.490 ± 0.017***
Rel. to Brain (g/g) 1.266 ± 0.041 1.276 ± 0.048 1.289 ± 0.040 1.142 ± 0.026* 1.002 ± 0.033*** 0.971 ± 0.037***
Rel. to Body (mg/g) 15.21 ± 0.509 15.10 ± 0.302 16.45 ± 0.362 14.28 ± 0.433* 12.74 ± 0.326*** 12.87 ± 0.388***
Liver
Absolute (g) 1.890 ± 0.089 2.044 ± 0.113 1.762 ± 0.049 (19) 1.896 ± 0.128 1.597 ± 0.076 1.493 ± 0.071*
Rel. to Brain (g/g) 3.484 ± 0.160 3.917 ± 0.230 3.363 ± 0.086 3.571 ± 0.235 3.065 ± 0.139 2.951 ± 0.150
Rel. to Body (mg/g) 41.03 ± 1.001 45.77 ± 1.332 42.83 ± 0.658 43.43 ± 1.591 38.67 ± 0.990 38.71 ± 0.913
Testes
Absolute (g) 0.256 ± 0.006 0.241 ± 0.008 0.269 ± 0.010 0.198 ± 0.015*** 0.236 ± 0.006 0.243 ± 0.007
Rel. to Brain (g/g) 0.472 ± 0.009 0.461 ± 0.016 0.512 ± 0.018 0.372 ± 0.028*** 0.454 ± 0.011 0.480 ± 0.014
Rel. to Body (mg/g) 2.834 ± 0.085 2.712 ± 0.126 3.303 ± 0.114 2.312 ± 0.194*** 2.911 ± 0.099 3.218 ± 0.161
Thyroid Gland
Absolute (g) 0.006 ± 0.0 0.006 ± 0.0 (17) 0.005 ± 0.001 0.004 ± 0.0** 0.004 ± 0.0** 0.004 ± 0.0**
Rel. to Brain (g/g) 0.011 ± 0.001 0.011 ± 0.001 0.010 ± 0.001 0.008 ± 0.0** 0.008 ± 0.0** 0.008 ± 0.0*
Rel. to Body (mg/g) 0.135 ± 0.011 0.137 ± 0.009 0.129 ± 0.015 0.101 ± 0.006** 0.100 ± 0.007** 0.111 ± 0.007**
a

Mean counts ± S.E.M., n = 20 except were indicated by numbers in parentheses.

Shaded cell indicates statistically significant difference from NIH-41 diet group;

*

p < 0.05,

**

p < 0.01,

***

p < 0.001.