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. 2016 Jul 4;10:132. doi: 10.3389/fnbeh.2016.00132

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Copyright © 2016 Genné-Bacon, Trinko and DiLeone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FosB/ΔFosB levels are increased specifically in the dorsomedial hypothalamus (DMH) following repeated mT exposure. FosB/ΔFosB immunofluorescent staining was carried out on perfused brain tissue from chronic scent-exposed mice. (A,B) Representative images of FosB/ΔFosB expression in the DMH in a BA or mT-exposed mouse brain, respectively. Dotted line represents DMH based on approximate brain region boundaries (C) from Paxinos and Franklin (2004); 3V, third ventricle, f, fornix, VMH, ventromedial hypothalamus, Arc, arcuate nucleus. Significantly more FosB/ΔFosB positive cells were counted in the DMH of chronically mT-exposed mice, compared to BA-exposed (D). Error bars shown represent SEM.