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UGT1A1 gene polymorphism and tumor response (n = 43)
| UGT1A1 | n | CR | PR | SD | PD | Response (%) | P |
|---|---|---|---|---|---|---|---|
| *6/*6 | 1 | 0 | 0 | 1 | 0 | 0 | — |
| *28/*6 | 1 | 0 | 1 | 0 | 0 | 100 | — |
| *28/− | 5 | 1 | 2 | 2 | 0 | 60 | 0.175 |
| *6/− | 16 | 0 | 9 | 7 | 0 | 56 | 0.312 |
| −/− | 20 | 1 | 5 | 12 | 2 | 30 | — |
P: compared with “−/−” by 2 × 2 Chi square & Fisher's test. CR, complete response; PD, progressive disease; PR, partial response; SD, stable disease; UGT1A1, uridine 5'‐diphospho‐glucuronosyltransferase 1A1.
