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. 2016 Jun 24;7:11939. doi: 10.1038/ncomms11939

Figure 4. Identification of bifidobacterial genes responsible for HMO utilization.

Figure 4

(a) Syntenic relationships of putative FL-utilization gene clusters identified among the bifidobacteria. The genes and their orientations are depicted with arrows. Strains lacking fucosidase genes (10 strains among 29) are not represented. (b) Growth curves of the B. breve BR-A29 strain and the corresponding FL-SBP gene knockout strain in medium containing HMOs. (c) Glycoprofiles of BR-A29 and FL-SBP gene-knockout strains after 40 h of cultivation.