Figure 2.

The optic vesicle is progressively epithelialized during morphogenesis in fish. Left schematic is a frontal view of the brain showing the evaginating optic vesicles. The blue dashes indicate the internal position of ventricular space within the optic vesicles and orange dots indicate abundant Laminin. The inset shows the organization of neuroepithelial cells in the evaginating optic vesicles. Cells at the margin of the eye field (pale green) show coordinated epithelial organization dependent upon contact with a Laminin-1 enriched basal lamina. Core cells (yellow) intercalate into the nascent epithelium aligning their apicobasal polarity and shape with their polarized neighbours during this process. Based on Ivanovitch et al. [5^••].