Table 1.
Symptoms | Mean ± SD | ||||||
---|---|---|---|---|---|---|---|
Baseline | D15 | P ∗∗ | D45 | P ∗∗∗ | D75 | P ∗∗∗∗ | |
Dryness | 9.5 ± 2.2 | 5.9 ± 3.5 | <0.01∗ | 4.1 ± 3.1 | <0.01∗ | 4.2 ± 3.0 | 1 |
Foreign body sensation | 8.0 ± 4.1 | 4.8 ± 3.9 | <0.01∗ | 3.5 ± 3.4 | 0.129 | 3.7 ± 3.2 | 1 |
Itching | 3.8 ± 4.9 | 1.8 ± 3.4 | 0.03 | 1.1 ± 2.6 | 0.54 | 1.0 ± 2.6 | 1 |
Burning | 3.8 ± 4.9 | 1.1 ± 2.8 | <0.01∗ | 0.9 ± 2.5 | 1 | 1.3 ± 2.8 | 0.93 |
Visual fatigue | 5.0 ± 5.1 | 3.5 ± 4.0 | 0.01∗ | 2.8 ± 3.4 | 0.24 | 2.5 ± 3.4 | 1 |
Blurred vision | 1.0 ± 3.1 | 0.7 ± 2.2 | 0.54 | 0.3 ± 1.5 | 1 | 0.2 ± 0.9 | 1 |
Sensitivity to light | 4.3 ± 5.0 | 2.3 ± 3.4 | <0.01∗ | 1.8 ± 3.1 | 0.45 | 1.6 ± 2.8 | 1 |
Watering | 2.5 ± 4.4 | 1.1 ± 2.8 | 0.02∗ | 0.8 ± 2.4 | 1 | 0.7 ± 1.9 | 1 |
Secretion disturbance | 5.8 ± 5.0 | 2.8 ± 3.3 | <0.01∗ | 2.7 ± 3.4 | 1 | 2.6 ± 3.8 | 1 |
Pain | 4.3 ± 5.0 | 2.8 ± 3.9 | 0.04∗ | 1.5 ± 2.7 | 0.03∗ | 1.6 ± 3.1 | 1 |
Notes: ∗ P < 0.05; ∗∗compared to baseline; ∗∗∗compared to D15; ∗∗∗∗compared to D45. Statistical analysis was performed with paired t-test with the Bonferroni correction.
SD: standard deviation; D: day.