Table 2.
Demographic and laboratory findings of patients with different types of organ involvement
| Items | (A) Only one type of organ involved | (B) Two types of organs involved | A + B | |||
|---|---|---|---|---|---|---|
| MD (n = 26) | Non-MD (n = 36) | With MD (n = 53) | Without MD (n = 30) | With MD (n = 79) | Without MD (n = 66) | |
| Duration (years) | 1.31 (0.85, 4.40)* | 0.56 (0.30, 0.96)* | 2.00 (1.00, 4.00)* | 0.38 (0.08, 1.12)* | 1.65 (0.88, 4.25)* | 0.50 (0.17, 1.00)* |
| Male:female | 12:14* | 27:8* | 26:27* | 26:4* | 38:41* | 53:12* |
| Age (years) | 47.6 ± 13.1 | 50.7 ± 15.1 | 53.7 ± 13.6 | 53.3 ± 16.5 | 51.7 ± 13.6 | 51.9 ± 15.7 |
| Allergy history, n/N (%) | 14/26 (53.8) | 15/36 (41.7) | 39/53 (73.6)* | 14/30 (46.7)* | 53/79 (67.1)* | 29/66 (43.9)* |
| Eosinophil (%) | 4.36 (1.93, 6.23) | 2.30 (1.15, 5.05) | 4.40 (2.30, 6.65)* | 1.20 (0.57, 3.07)* | 4.37 (2.15, 6.32)* | 2.15 (0.93, 4.33)* |
| ESR | 15.0 (4.2, 28.0)* | 35.0 (12.7, 70.7)* | 17.5 (6.2, 63.7) | 38.5 (11.5, 80.7) | 17.2 (6.2, 56.0) | 36.5 (12.7, 73.5) |
| CRP (mg/L) | 2.03 (0.85, 7.36) | 5.01 (1.96, 13.51) | 1.45 (0.42, 4.28)* | 8.45 (2.37, 38.58)* | 1.50 (0.64, 5.46)* | 7.52 (2.52, 24.81)* |
| IgG (g/L) | 22.2 ± 10.3 | 19.0 ± 7.7 | 23.5 ± 12.6 | 21.9 ± 15.0 | 23.5 ± 12.6 | 21.9 ± 15.0 |
| IgA (g/L) | 1.6 ± 0.7* | 2.9 ± 1.6* | 1.8 ± 0.9* | 2.5 ± 1.5* | 1.8 ± 0.8* | 2.7 ± 1.5* |
| IgM (g/L) | 1.2 ± 1.3 | 1.54 ± 1.85 | 0.85 ± 0.5 | 0.9 ± 0.5 | 0.95 ± 0.8 | 1.2 ± 1.4 |
| IgG1 (g/L) | 0.98 ± 0.50 | 1.08 ± 0.59 | 0.96 ± 0.48 | 1.25 ± 1.15 | 0.96 ± 0.48 | 1.16 ± 0.89 |
| IgG2 (g/L) | 0.68 ± 0.48 | 0.63 ± 0.29 | 0.54 ± 0.23 | 0.63 ± 0.30 | 0.59 ± 0.34 | 0.63 ± 0.29 |
| IgG3 (g/L) | 0.54 (0.37, 1.16)* | 0.31 (0.21, 0.53)* | 0.44 (0.24, 0.94) | 0.59 (0.23, 1.25) | 0.53 (0.30, 0.97) | 0.42 (0.22, 0.78) |
| IgG4 (g/L) | 11.25 (3.78, 16.83)* | 3.26 (1.74, 6.66)* | 10.80 (4.73, 21.20)* | 4.02 (2.61, 9.92)* | 11.00 (4.63, 18.22)* | 3.71 (2.02, 7.53)* |
| IgE (kU/L) | 163.5 (36.9, 462.0) | 180.0 (88.7, 509.2) | 537.0 (203.0, 1130.0) | 377.0 (128.5, 906.0) | 526.3 (207.5, 921.5) | 262.0 (118.2, 845.7) |
| IgG4/IgG (%) | 57.86 (25.74, 70.29)* | 17.55 (10.84, 30.62)* | 61.63 (30.11, 81.37)* | 24.62 (15.89, 44.26)* | 61.35 (29.57, 80.60)* | 21.07 (12.82, 36.44)* |
*P<0.05. P value was determined by Fisher's exact test (categorical), Student's t-test (parametric) and nonparametric tests (nonparametric); parametric test values were shown as mean ± SD, and nonparametric test values were shown as median (percentiles 25, percentiles 75); MD: Mikulicz's disease; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; Ig: Immunoglobulin.