Table 2. Hazard ratios and 95% confidence intervals representing the association between recreational physical inactivity and mortality among women diagnosed with invasive EOC (N=6806; 12 studies)a.
|
95% CI |
|||||||
|---|---|---|---|---|---|---|---|
| EOC histology | Modelb | N (events) | N (censored) | HR | Lower | Upper | P-value |
| All EOC casesc | Age-adjusted | 2898 | 3907 | 1.13 | 1.04 | 1.22 | 0.005 |
| Multivariable | 2861 | 3876 | 1.22 | 1.12 | 1.33 | <0.001 | |
| Invasive high-grade serousd | Age-adjusted | 2287 | 1902 | 1.16 | 1.05 | 1.27 | 0.002 |
| Multivariable | 2281 | 1900 | 1.21 | 1.11 | 1.33 | <0.001 | |
| Invasive low-grade serousd | Age-adjusted | 104 | 213 | 1.16 | 0.77 | 1.75 | 0.479 |
| Multivariable | 103 | 213 | 1.30 | 0.89 | 1.96 | 0.219 | |
| Invasive mucinousd | Age-adjusted | 85 | 380 | 1.21 | 0.77 | 1.91 | 0.410 |
| Multivariable | 85 | 379 | 0.93 | 0.59 | 1.49 | 0.773 | |
| Invasive endometrioidd | Age-adjusted | 225 | 943 | 1.14 | 0.85 | 1.53 | 0.395 |
| Multivariable | 225 | 943 | 1.26 | 0.94 | 1.70 | 0.125 | |
| Invasive clear celld | Age-adjusted | 167 | 441 | 1.30 | 0.93 | 1.80 | 0.125 |
| Multivariable | 167 | 441 | 1.29 | 0.92 | 1.79 | 0.136 | |
Abbreviations: CI=confidence interval; EOC=epithelial ovarian cancer; HR=hazard ratio.
Numbers may not sum to total due to missing data.
Adjustment variables were identified based on well-established prognostic factors for EOC and the 10% change-in-estimate method.
Multivariable model is adjusted for age, stage, and histotype.
Multivariable model is adjusted for age and stage.