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. 2016 Jul 4;6:28890. doi: 10.1038/srep28890

Figure 7. Quick-view mutational analysis reveals PC4’s influence on hypermutation of a constitutively expressed transgene (GFP).

Figure 7

Cells were sorted for GFP (+) in the AIDr1 ψv- IgL-Pro−/GFP (a) and AIDr1 ψv- ΔPC4 IgL-Pro−/GFP (b) clones. Following two weeks bulk growth of the sorted population, gDNA was recovered from each and the GFP gene was sequenced for a more complete analysis. Insertions and deletions are displayed as green and red circles, respectively, and transitions and transversions as blue and gold diamonds, respectively.