Table 3. Antimicrobial resistance determinants of S. flexneri serotype 4s isolates.
| No. | β-Lactamases gene and type |
QRDR (or outside) mutation |
PMQR gene |
Integrons and gene cassette array |
|||||
|---|---|---|---|---|---|---|---|---|---|
| blaOXA-1 | blaTEM-1 | blaCTX | gyrA | parC | qnrS | aac(6′)-Ib-cr | IntI1 | IntI2 | |
| BJ4s01 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| BJ4s02 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| BJ4s03 | + | + | − | S83L, H211Y | S80I | + | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| BJ4s04 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| BJ4s05 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| GX4s01 | + | + | blaCTX-M-14 | S83L, H211Y | S80I | + | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| GX4s02 | + | + | − | S83L, H211Y | S80I | - | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| GX4s03 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| GX4s04 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| GX4s05 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| HN4s01 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| HN4s02 | + | + | blaCTX-M-14 | S83L, H211Y | S80I | − | − | dfrA17 + aadA5 | dfrA1 + sat1 + aadA1 |
| HN4s03 | + | + | blaCTX-M-79 | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| HN4s04 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| HN4s05 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| HN4s06 | + | + | blaCTX-M-14 | S83L, H211Y | S80I | + | + | aacA4 + cmlA1 | dfrA1 + sat1 + aadA1 |
| SH4s01 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s02 | + | + | blaCTX-M-14 | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s04 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s05 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s06 | + | + | blaCTX-M-14 | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s07 | + | + | blaCTX-M-14 | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s08 | + | + | − | S83L, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |
| SH4s09 | + | + | − | S83L, S87N, H211Y | S80I | − | − | blaOXA1 + aadA2 | dfrA1 + sat1 + aadA1 |