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. Author manuscript; available in PMC: 2016 Jul 4.
Published in final edited form as: Physiology (Bethesda). 2012 Dec;27(6):351–361. doi: 10.1152/physiol.00026.2012

FIGURE 1. A modeled CFTR structure.

FIGURE 1

Side views of a homology model of CFTR based on the prokaryotic ABC exporter, Sav1866 (54). Gray, TMDs; purple, NBD1; blue, NBD2. Three residues in TM6 mentioned in this review (from top to bottom: I344, M348, R352) are labeled in red. G551 in NBD1 is labeled in green. E1371 in NBD2 is labeled in red (courtesy of Dr. David Dawson).