Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 4;6:28993. doi: 10.1038/srep28993

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

An antibody against CRALBP was used to stain Müller cells. (A–D) ZEB2 was expressed in the ganglion cell layer (GCL), the inner nuclear layer (INL) and the outer plexiform layer (OPL) but hardly detected in the outer nuclear layer (ONL) in the wild type (WT) retina. The small arrows in B point to Müller cell bodies in the INL. (E–H) Transgenic (TG) retina collected 3 months after induced Müller cell disruption. Increased immunoreactivity for ZEB2 was observed in the outer retina where Müller cell ablation resulted in defects is the outer limiting membrane (small arrows in E–G) through which degenerating photoreceptor cell bodies protruded into the subretinal space (large arrows in H). (D,H) are higher power images of the outer retina in (C,G) respectively. RPE = retinal pigment epithelium. Scale bars: 50 μm.