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. 2016 Jul 4;6:28993. doi: 10.1038/srep28993

Figure 6. The impact of intravitreal injections of miR-200b mimic and anti-miR-200b on ZEB2, VEGF-A and FLT1 expression.

Figure 6

Western blots for ZEB2 (A), VEGF-A (B) and FLT1 (C) were conducted using retinas collected 10 days after intravitreal injections of miR-200b mimic, anti-miR-200b and a scramble miRNA (control). miR-200b mimic significantly suppressed ZEB2 and tended to inhibit VEGF-A and FLT1 expression whereas anti-miR-200b significantly increased ZEB2 and VFGE-A and tended to increase FLT1 expression. The effects of miR-200b regulators on these proteins were more marked when the values of the miR-200b mimic and anti-miR-200b injected groups were compared directly. *P < 0.05, scrambled vs miR-mimic or anti-miR; †P < 0.05 and ‡P < 0.01, miR-200b mimic vs anti-miR200b; n = 8 in miR-200b mimic group and n = 10 in anti-miR-200b group.