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. 2016 Jun 21;6(6):e840. doi: 10.1038/tp.2016.100

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Copyright © 2016 Macmillan Publishers Limited

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Localizations of the stimulation electrodes. (a) Coronal sections from the caudal to rostral regions of the nucleus accumbens (NAc) showing desired target region (red) and localizations of the tip of the stimulation electrodes (black) within the NAcs in alcohol-dependent continuously stimulated rats. (b) Negative correlation (Rho=0.60; P<0.01) between the distance of each electrode tip to the desired target within the NAcs and individual alcohol intake in alcohol-dependent continuously stimulated rats. Respective delta ethanol intake was calculated by subtracting average ethanol intake of the first four alcohol-deprivation effect (ADE) days from that of the last four baseline days.