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. 2016 Jun 28;6(6):e845. doi: 10.1038/tp.2016.107

Table 2. The effects of ASD traits and anxiety on BOLD responses during reward anticipation.

      Peak MNI coordinates
   
Region Brodmann area Cluster size (voxels) x y z Z P (FWE)
               
Interaction: ASD traits x anxiety
 R middle and superior temporal gyri, R insula 21/22/13 283 45 −16 −11 3.97 0.001
      57 −37 −8 3.80  
      63 −16 −11 3.71  
               
High<low ASD traits
 R superior and medial frontal gyri extending bilaterally to the dACC and MCC 9/24/32 936 −18 17 37 4.88 <0.001
      18 17 49 4.72  
      9 50 37 4.58  
               
Any anxiety>no anxiety
 R middle frontal gyrus 8 254 39 23 43 4.41 0.002
      21 59 37 3.89  
      42 8 49 3.66  
 R middle temporal gyrus 21 209 45 −16 −11 3.98 0.008
      60 −16 −5 3.67  
      57 −37 −11 3.47  
               
ASDANX>ASDONLY
 R middle temporal gyrus 21 257 57 −37 −8 4.56 <0.001
      63 −13 −2 4.31  
      69 −37 −2 3.90  
 R middle frontal gyrus 8 251 42 23 43 4.27 <0.001
      42 11 52 3.71  
      42 32 43 3.45  
 L insula, L inferior frontal gyrus 13/45/47 162 −42 17 −11 4.27 0.011
      −36 17 1 3.43  
      −45 17 7 3.36  
 L inferior parietal lobule 40 124 −57 −43 55 3.86 0.047
      −48 −61 52 3.33  
      −66 −37 37 3.11  
 L superior and middle temporal gyri 39/22/40 246 −60 −67 7 3.71 0.001
      −51 −82 7 3.70  
      −51 −79 22 3.68  
 R inferior parietal lobule 40 256 51 −52 55 3.60 <0.001
      60 −34 55 3.49  
      48 −34 64 3.41  
               
ASDANX>ANXONLY
 L insula, L inferior frontal gyrus 47 186 −42 17 −8 4.68 0.017
      −36 14 4 3.65  
      −54 20 1 3.57  
 L and R cuneus and calcarine 18/17 222 −12 −82 10 4.30 0.006
      12 −85 10 3.77  
      −6 −76 22 3.38  

Abbreviations: ANXONLY, high anxiety and low ASD traits; ASD, autism spectrum disorder; ASDANX, high ASD traits and anxiety; ASDONLY, high ASD traits, low anxiety; BOLD, blood-oxygen-level dependent; dACC, dorsal anterior cingulate cortex; FWE, family-wise error correction; L, left hemisphere; MCC, middle cingulate cortex; MNI, Montreal Neurological Institute; R, right hemisphere.