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editorial
. 2016 Jun 28;6(6):e847. doi: 10.1038/tp.2016.108

Table 3. Summary of the rates of exclusion because of each exclusion criterion applied in in treatment studies of anxiety disorders.

  Reviews of rates of exclusion
Review paper Odlaug19 Hoertel20 Hoertel21 Hoertel21 Hoertel23 Hoertel23
Year range of studies reviewed 1980–2010 1898–2004 1980–2009 1980–2009 1979–2007 1979–2007
Disorder OCD PD GAD GAD SO SO
Type of treatment Pharmacotherapy Pharmacotherapy and psychotherapy Pharmacotherapy Psychotherapy Pharmacotherapy Psychotherapy
Number of participants 325 105a 329a 329a 363a 363a
             
Exclusion criteria Rates of exclusion reported in each review according to each exclusion criterion
Other psychiatric disorders
 Axis I disorder            
 MDD 16.3% 70.6% 62.8% 62.8% 60.4% 60.4%
 Suicide risk         5.9%  
 Bipolar disorder 3.1% 58.9% 20.0%   42.6% 42.6%
 Psychosis 2.8% 21.2% 5.9% 5.9% 14.5% 14.5%
 Axis II disorders            
 Avoidant personality disorder            
 Antisocial personality disorder     10.4%      
             
Alcohol abuse/dependence
 Alcohol abuse/dependence 5.2% 61.5% 12.9%   16.4% 16.4%
 Drug abuse/dependence 5.2% 61.5% 5.7%   8.7% 8.7%
 Substance abuse/dependence 5.2% 61.5%        
             
Treatments
 Current psychotherapy            
 Recent medication changes            
 Current pharmacotherapy            
 History of treatment            
             
Other specific anxiety disorders
 Panic disorder       36.4% 37.6%  
 Agoraphobia            
 Eating disorder            
 OCD            
 Specific and social phobia       47.5%    
             
Other medical conditions
 Major medical condition   34.3% 19.4%   25.3%  
 Organic disorder            
 Serious comorbidity            
 Exclusion of low severity 28.9%          
 Pregnancy     3.1%   2.2%  
% Excluded for at least 1 exclusion criteria 72.0% 92.4% 81.8% 82.1% 87.8% 80.5%

Abbreviations: GAD, generalized anxiety disorder; MDD, major depressive disorder; OCD, obsessive-compulsive disorder; PD, panic disorder; SO, social phobia.

a

Percentages are out of the treatment-seeking sample.