Table 2. Reduced connectivity in depressive patients with suicidal ideation found using the NBS analysis compared with depressive patients without ideation.
Edges | t-statisticsa |
Mean edge strength |
Correlation coefficients in MDD with suicidal ideationb |
||||
---|---|---|---|---|---|---|---|
Suicidal ideation | No suicidal ideation | SSI | BIS motor | BIS attention-cognitive | BIS non-planning | ||
Left rostral middle frontalc and left pallidumc | 3.01 | 5.04 | 40.68 | −0.24 | −0.08 | −0.28 | −0.27 |
Left rostral middle frontalc and left lateral occipital | 2.52 | 0.54 | 5.32 | 0.23 | −0.13 | 0.27 | 0.27 |
Left rostral middle frontalc and left pars orbitalis | 2.44 | 50.67 | 98.40 | 0.40 | 0.73d | 0.20 | 0.21 |
Left superior parietalc and left thalamus | 3.21 | 14.08 | 58.52 | 0.25 | 0.21 | 0.02 | 0.17 |
Left superior parietalc and left putamen | 2.94 | 81.25 | 162.76 | −0.15 | −0.04 | −0.22 | −0.10 |
Left superior parietalc and left pallidumc | 2.25 | 17.00 | 41.60 | −0.44 | −0.39 | −0.26 | −0.42 |
Left pars triangularis and left putamen | 2.37 | 27.75 | 78.16 | −0.27 | −0.56d | 0.13 | −0.19 |
Left frontal pole and left caudate | 2.37 | 10.50 | 43.12 | −0.18 | 0.00 | −0.29 | −0.21 |
Left frontal pole and left pallidumc | 2.34 | 0 | 3.92 | NA | NA | NA | NA |
Abbreviations: BIS, Barrett Impulsiveness Scale; FDR, false discovery rate; MDD, major depressive disorder; NA, not available; NBS, network-based statistics; SSI, Scale for Suicide Ideation.
Student's t-statistic from two-sample t-test, (MDDwithout−MDDwith).
Correlation coefficients between edge weights and SSI/BIS scores in MDD with suicidal ideation.
Hub nodes.
Bold, significant after FDR correction over nine edges.