Table 2.
Demographics and PD characteristics by time to initiation of ST
| Variable | All PD | PD Subjects | PD Subjects | PD Subjects | PD Subjects | PD Subjects |
|---|---|---|---|---|---|---|
| Subjects | ST− | ST+ ≤6 Month | ST+ 6 Mo‐1 Year | ST+ 1–2 Years | ST+ >2 Years | |
| (N = 423) | (N = 139) | (N = 92) | (N = 118) | (N = 65) | (N = 9) | |
| Age | ||||||
| Mean (SD) | 61.66 (9.7) | 61.69 (10.3) | 60.94 (9.9) | 62.06 (9.3) | 61.92 (9.6) | 61.52 (5.0) |
| (Min, Max) | (33.5, 84.9) | (33.5, 82.3) | (38.5, 80.2) | (33.7, 84.9) | (36.6, 83.0) | (51.7, 66.6) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Gender | ||||||
| Male | 277 (65.48%) | 87 (62.59%) | 60 (65.22%) | 84 (71.19%) | 39 (60.00%) | 7 (77.78%) |
| Female | 146 (34.52%) | 52 (37.41%) | 32 (34.78%) | 34 (28.81%) | 26 (40.00%) | 2 (22.22%) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Education | ||||||
| <13 Years | 76 (17.97%) | 34 (24.46%) | 18 (19.57%) | 15 (12.71%) | 9 (13.85%) | 0 (0.00%) |
| 13–23 Years | 344 (81.32%) | 104 (74.82%) | 74 (80.43%) | 102 (86.44%) | 55 (84.62%) | 9 (100.00%) |
| >23 Years | 3 (0.71%) | 1 (0.72%) | 0 (0.00%) | 1 (0.85%) | 1 (1.54%) | 0 (0.00%) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Ethnicity | ||||||
| Hispanic/latino | 9 (2.13%) | 2 (1.44%) | 1 (1.09%) | 3 (2.54%) | 1 (1.54%) | 2 (22.22%) |
| Not Hispanic/latino | 414 (97.87%) | 137 (98.56%) | 91 (98.91%) | 115 (97.46%) | 64 (98.46%) | 7 (77.78%) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Race | ||||||
| White | 391 (92.43%) | 130 (93.53%) | 85 (92.39%) | 109 (92.37%) | 58 (89.23%) | 9 (100.00%) |
| Black/African‐American | 6 (1.42%) | 2 (1.44%) | 1 (1.09%) | 3 (2.54%) | 0 (0.00%) | 0 (0.00%) |
| Asian | 8 (1.89%) | 1 (0.72%) | 4 (4.35%) | 1 (0.85%) | 2 (3.08%) | 0 (0.00%) |
| Other | 18 (4.26%) | 6 (4.32%) | 2 (2.17%) | 5 (4.24%) | 5 (7.69%) | 0 (0.00%) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Family history of PD | ||||||
| Family members w/PD | 102 (24.17%) | 30 (21.74%) | 24 (26.09%) | 26 (22.03%) | 20 (30.77%) | 2 (22.22%) |
| No Family members w/PD | 320 (75.83%) | 108 (78.26%) | 68 (73.91%) | 92 (77.97%) | 45 (69.23%) | 7 (77.78%) |
| Missing | 1 | 1 | 0 | 0 | 0 | 0 |
| MDS‐UPDRS mean (SD) score and subscores | ||||||
| MDS‐UPDRS total score | 32.36 (13.1) | 27.90 (12.0) | 36.58 (14.2) | 34.97 (13.0) | 31.51 (11.5) | 30.11 (10.9) |
| MDS‐UPDRS part I | 5.57 (4.1) | 4.94 (4.1) | 6.27 (4.0) | 5.86 (4.0) | 5.62 (4.1) | 4.11 (2.9) |
| MDS‐UPDRS part II | 5.90 (4.2) | 4.64 (3.4) | 7.74 (4.5) | 6.58 (4.7) | 5.02 (3.4) | 4.22 (2.9) |
| MDS‐UPDRS part III (motor exam) | 20.89 (8.9) | 18.32 (8.4) | 22.57 (10.0) | 22.57 (8.2) | 20.88 (8.4) | 21.78 (7.4) |
| Missing | 1 | 0 | 0 | 1 | 0 | 0 |
| Hoehn and Yahr | ||||||
| Stage 1 | 186 (43.97%) | 68 (48.92%) | 40 (43.48%) | 42 (35.59%) | 30 (46.15%) | 6 (66.67%) |
| Stage 2 | 235 (55.56%) | 71 (51.08%) | 51 (55.43%) | 75 (63.56%) | 35 (53.85%) | 3 (33.33%) |
| Stage 3–5 | 2 (0.47%) | 0 (0.00%) | 1 (1.09%) | 1 (0.85%) | 0 (0.00%) | 0 (0.00%) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Modified Schwab and England ADL | ||||||
| Mean (SD) | 93.15 (5.9) | 95.35 (5.5) | 90.22 (6.1) | 92.54 (5.3) | 93.85 (5.6) | 92.22 (3.6) |
| (Min, Max) | (70.0, 100.0) | (75.0, 100.0) | (70.0, 100.0) | (80.0, 100.0) | (80.0, 100.0) | (90.0, 100.0) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Duration of disease since diagnosis (Mon) | ||||||
| Mean (SD) | 6.65 (6.5) | 6.32 (5.6) | 5.56 (4.7) | 6.59 (7.0) | 8.56 (8.7) | 10.14 (8.2) |
| (Min, Max) | (0.4, 35.8) | (0.9, 32.3) | (0.9, 25.7) | (0.7, 31.9) | (0.4, 35.8) | (1.0, 23.0) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Age of PD Diagnosis | ||||||
| Mean (SD) | 61.11 (9.7) | 61.17 (10.2) | 60.48 (9.9) | 61.51 (9.3) | 61.21 (9.6) | 60.68 (5.6) |
| (Min, Max) | (31.8, 84.8) | (33.0, 81.8) | (38.4, 80.0) | (31.8, 84.8) | (35.8, 81.7) | (49.8, 65.7) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| TD/Non‐TD classification | ||||||
| TD | 299 (70.85%) | 98 (70.50%) | 58 (63.04%) | 85 (72.65%) | 52 (80.00%) | 6 (66.67%) |
| PIGD or Indeterminate | 123 (29.15%) | 41 (29.50%) | 34 (36.96%) | 32 (27.35%) | 13 (20.00%) | 3 (33.33%) |
| Missing | 1 | 0 | 0 | 1 | 0 | 0 |
| PIGD sum score | ||||||
| Mean (SD) | 0.23 (0.2) | 0.19 (0.2) | 0.29 (0.3) | 0.23 (0.2) | 0.20 (0.2) | 0.24 (0.2) |
| (Min, Max) | (0.0, 1.4) | (0.0, 1.2) | (0.0, 1.4) | (0.0, 1.0) | (0.0, 0.6) | (0.0, 0.6) |
| Missing | 1 | 0 | 0 | 1 | 0 | 0 |
| Tremor Sum Score | ||||||
| Mean (SD) | 0.49 (0.3) | 0.43 (0.3) | 0.49 (0.4) | 0.55 (0.3) | 0.54 (0.3) | 0.52 (0.4) |
| (Min, Max) | (0.0, 1.8) | (0.0, 1.3) | (0.0, 1.8) | (0.0, 1.6) | (0.0, 1.3) | (0.0, 1.1) |
| Missing | 1 | 0 | 0 | 1 | 0 | 0 |
| Side most affected | ||||||
| Left | 180 (42.55%) | 57 (41.01%) | 42 (45.65%) | 52 (44.07%) | 26 (40.00%) | 3 (33.33%) |
| Right | 233 (55.08%) | 79 (56.83%) | 47 (51.09%) | 64 (54.24%) | 37 (56.92%) | 6 (66.67%) |
| Symmetric | 10 (2.36%) | 3 (2.16%) | 3 (3.26%) | 2 (1.69%) | 2 (3.08%) | 0 (0.00%) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Time enrolled in study (Years) | ||||||
| Mean (SD) | 2.11 (0.8) | 1.79 (0.7) | 2.03 (0.8) | 2.29 (0.8) | 2.45 (0.7) | 3.08 (0.5) |
| (Min, Max) | (0.0, 4.1) | (0.0, 3.5) | (0.0, 4.1) | (1.0, 4.1) | (1.2, 3.8) | (2.3, 3.7) |
| Missing | 0 | 0 | 0 | 0 | 0 | 0 |
| Time to initiate ST (Years) | ||||||
| Mean (SD) | NA | NA | 0.36 (0.1) | 0.66 (0.1) | 1.37 (0.3) | 2.53 (0.5) |
| (Min, Max) | NA | NA | (0.0, 0.5) | (0.5, 1.0) | (1.0, 2.0) | (2.0, 3.3) |
| Missing | NA | NA | 0 | 0 | 0 | 0 |
Report generated on data submitted as of: 15 September 2014.
Please refer to Table 1 for abbreviations. See Discussion in the text.